Functional medicine tests for the prevention of disease

Menopause™ is a salivary hormone test for evaluating levels of sex hormones in both women and men. In this hormone test, three specimens — collected over 5 days — are examined for levels of estradiol, estrone, estriol, progesterone, the progesterone/estradiol ratio (P/E2), and testosterone. Hormone imbalances can be associated with common symptoms such as:

  • Hot flashes
  • Mood instability
  • Anxiety
  • Fatigue
  • Cognition
  • Weight gain
  • Low sex drive and performance issues
  • Sleep disturbances
  • Altered fat metabolism
  • Altered blood-sugar control
  • Vaginal atrophy
  • Hair Loss
Learn more

The Rhythm hormone test is a comprehensive assessment of estradiol, progesterone, and testosterone spanning a full 28 days. Hormone imbalances revealed in this hormone test profile can help illuminate root causes of disorders such as premenstrual syndrome (PMS), infertility, and menstrual irregularities. This hormonal test analyzes 11 saliva samples of a 28–day period.  Fluctuating levels of estradiol, progesterone, and testosterone play a major role in a woman’s overall health affecting:

  • Menstrual cycle
  • Mood swings
  • Sleep patterns
  • Appetite level
  • Sex drive
Learn more

The Rhythm Plus™ hormone test is a comprehensive salivary assessment of estradiol, progesterone, and testosterone that spans a full 28 days. Additionally, this hormone testing profile includes the Adrenocortex Stress Profile or Cortisol Awakening Response and the Comprehensive Melatonin Profile to reveal how the sex hormones are influenced by cortisol, DHEA, and melatonin.

As an added benefit, practitioners can select either an Adrenal Cortex Stress Profile Panel or Cortisol Awakening Response Panel to be run at no additional cost. If both are preferred, there will be an additional fee.

Hormone imbalances may be responsible for:

  • Menstrual cycle irregularities
  • Mood disorders
  • Insomnia
  • GI complaints
  • Libido
  • Fatigue
Learn more

The One Day Hormone Check™ is a convenient salivary hormone test that evaluates unbound, bioavailable hormone levels over 24 hours. Specimens collected over 24 hours are examined for levels of estradiol, estrone, estriol, progesterone, the progesterone/estradiol ratio (P/E2), testosterone, cortisol, DHEA, and melatonin.

Patients with hormone imbalance may present with:

  • Fatigue
  • Weight loss or gain
  • Menstrual irregularities
  • Loss of libido
  • Insomnia
  • Changes in hair and skin
  • Hot flashes

As an added benefit, practitioners can select either an Adrenal Cortex Stress Profile Panel or Cortisol Awakening Response Panel to be run at no additional cost. If both are preferred, there will be an additional fee.

Learn more

Menopause Plus™ is Genova’s most comprehensive salivary hormone test for evaluating key hormone levels in both women and men. Eight specimens – collected over six days – are examined for levels of estradiol, estrone, estriol, progesterone, the progesterone/estradiol ratio (P/E2), and testosterone. In addition to thorough evaluation of the sex hormones, Menopause Plus hormone test also evaluates DHEA, cortisol, and melatonin for the broadest scope of clinical insight. Hormones imbalances can be associated with common symptoms such as:

  • Hot flashes
  • Fatigue
  • Weight loss or gain
  • Menstrual irregularities
  • Loss of libido
  • Changes in hair and skin

As an added benefit, practitioners can select either an Adrenal Cortex Stress Profile Panel or Cortisol Awakening Response Panel to be run at no additional cost. If both are preferred, there will be an additional fee.

Learn more

Cortisol Awakening Response (CAR): Three awakening samples to evaluate CAR with one evening cortisol sample.

  • CAR is a transient, immediate rise in cortisol upon awakening and is distinct from the diurnal rhythm. CAR reflects a person’s ability to cope with anticipated challenges and their perception of control around chronic stress, providing insight into HPA axis resiliency.
  • The isolated evening cortisol has distinct clinical implications. Elevated evening cortisol is linked to insomnia and associated with various diseases such as diabetes, cardiovascular disease, hormonally driven cancers, and osteoporosis.
Learn more

The Adrenocortex Stress Profile (ASP) provides an assessment of the Hypothalamic-Pituitary-Adrenal (HPA) axis using carefully timed salivary samples of the hormones cortisol and DHEA. Salivary testing is an easy, non-invasive option to measure unbound, biologically active parent hormone levels. The report offers an easy-to-interpret graphic which plots the results of the Cortisol Awakening Response (CAR) and the natural diurnal rhythm, providing insight into HPA axis resiliency. HPA axis dysfunction is associated with many conditions including:

  • hypertension
  • cardiovascular disease
  • gastrointestinal and immune dysregulation
  • diabetes and metabolic syndrome
  • depression
  • chronic fatigue
  • persistent pain
  • neurodegenerative disease and cognitive decline
Learn more

Male Hormones Plus is a noninvasive salivary hormone assessment of bioavailable testosterone in circadian rhythm.

In addition to analysis of testosterone, Male Hormones Plus includes the Adrenocortex Stress Profile or Cortisol Awakening Response and the Comprehensive Melatonin Profile to reveal how testosterone is influenced by cortisol, DHEA, and melatonin.

As an added benefit, practitioners can select either an Adrenal Cortex Stress Profile Panel or Cortisol Awakening Response Panel to be run at no additional cost. If both are preferred, there will be an additional fee.

Learn more

The Choice is Yours. EndoSelect Salivary allows clinicians to order the salivary endocrine biomarkers designed for their patient’s unique needs, including:

  • Estradiol
  • Estriol*
  • Estrone*
  • Testosterone
  • Progesterone
  • DHEA
  • Cortisol 7AM-9AM
  • Cortisol 11AM-1PM
  • Cortisol 3PM-5PM
  • Cortisol 10PM-12AM
  • P/E2 Ratio and DHEA/Cortisol Ratio are included if the specific biomarkers are selected
Learn more

Menopause™ is a salivary hormone test for evaluating levels of sex hormones in both women and men. In this hormone test, three specimens — collected over 5 days — are examined for levels of estradiol, estrone, estriol, progesterone, the progesterone/estradiol ratio (P/E2), and testosterone. Hormone imbalances can be associated with common symptoms such as:

  • Hot flashes
  • Mood instability
  • Anxiety
  • Fatigue
  • Cognition
  • Weight gain
  • Low sex drive and performance issues
  • Sleep disturbances
  • Altered fat metabolism
  • Altered blood-sugar control
  • Vaginal atrophy
  • Hair Loss
Learn more

The Rhythm hormone test is a comprehensive assessment of estradiol, progesterone, and testosterone spanning a full 28 days. Hormone imbalances revealed in this hormone test profile can help illuminate root causes of disorders such as premenstrual syndrome (PMS), infertility, and menstrual irregularities. This hormonal test analyzes 11 saliva samples of a 28–day period.  Fluctuating levels of estradiol, progesterone, and testosterone play a major role in a woman’s overall health affecting:

  • Menstrual cycle
  • Mood swings
  • Sleep patterns
  • Appetite level
  • Sex drive
Learn more

The Rhythm Plus™ hormone test is a comprehensive salivary assessment of estradiol, progesterone, and testosterone that spans a full 28 days. Additionally, this hormone testing profile includes the Adrenocortex Stress Profile or Cortisol Awakening Response and the Comprehensive Melatonin Profile to reveal how the sex hormones are influenced by cortisol, DHEA, and melatonin.

As an added benefit, practitioners can select either an Adrenal Cortex Stress Profile Panel or Cortisol Awakening Response Panel to be run at no additional cost. If both are preferred, there will be an additional fee.

Hormone imbalances may be responsible for:

  • Menstrual cycle irregularities
  • Mood disorders
  • Insomnia
  • GI complaints
  • Libido
  • Fatigue
Learn more

The One Day Hormone Check™ is a convenient salivary hormone test that evaluates unbound, bioavailable hormone levels over 24 hours. Specimens collected over 24 hours are examined for levels of estradiol, estrone, estriol, progesterone, the progesterone/estradiol ratio (P/E2), testosterone, cortisol, DHEA, and melatonin.

Patients with hormone imbalance may present with:

  • Fatigue
  • Weight loss or gain
  • Menstrual irregularities
  • Loss of libido
  • Insomnia
  • Changes in hair and skin
  • Hot flashes

As an added benefit, practitioners can select either an Adrenal Cortex Stress Profile Panel or Cortisol Awakening Response Panel to be run at no additional cost. If both are preferred, there will be an additional fee.

Learn more

Menopause Plus™ is Genova’s most comprehensive salivary hormone test for evaluating key hormone levels in both women and men. Eight specimens – collected over six days – are examined for levels of estradiol, estrone, estriol, progesterone, the progesterone/estradiol ratio (P/E2), and testosterone. In addition to thorough evaluation of the sex hormones, Menopause Plus hormone test also evaluates DHEA, cortisol, and melatonin for the broadest scope of clinical insight. Hormones imbalances can be associated with common symptoms such as:

  • Hot flashes
  • Fatigue
  • Weight loss or gain
  • Menstrual irregularities
  • Loss of libido
  • Changes in hair and skin

As an added benefit, practitioners can select either an Adrenal Cortex Stress Profile Panel or Cortisol Awakening Response Panel to be run at no additional cost. If both are preferred, there will be an additional fee.

Learn more

Cortisol Awakening Response (CAR): Three awakening samples to evaluate CAR with one evening cortisol sample.

  • CAR is a transient, immediate rise in cortisol upon awakening and is distinct from the diurnal rhythm. CAR reflects a person’s ability to cope with anticipated challenges and their perception of control around chronic stress, providing insight into HPA axis resiliency.
  • The isolated evening cortisol has distinct clinical implications. Elevated evening cortisol is linked to insomnia and associated with various diseases such as diabetes, cardiovascular disease, hormonally driven cancers, and osteoporosis.
Learn more

The Adrenocortex Stress Profile (ASP) provides an assessment of the Hypothalamic-Pituitary-Adrenal (HPA) axis using carefully timed salivary samples of the hormones cortisol and DHEA. Salivary testing is an easy, non-invasive option to measure unbound, biologically active parent hormone levels. The report offers an easy-to-interpret graphic which plots the results of the Cortisol Awakening Response (CAR) and the natural diurnal rhythm, providing insight into HPA axis resiliency. HPA axis dysfunction is associated with many conditions including:

  • hypertension
  • cardiovascular disease
  • gastrointestinal and immune dysregulation
  • diabetes and metabolic syndrome
  • depression
  • chronic fatigue
  • persistent pain
  • neurodegenerative disease and cognitive decline
Learn more

Male Hormones Plus is a noninvasive salivary hormone assessment of bioavailable testosterone in circadian rhythm.

In addition to analysis of testosterone, Male Hormones Plus includes the Adrenocortex Stress Profile or Cortisol Awakening Response and the Comprehensive Melatonin Profile to reveal how testosterone is influenced by cortisol, DHEA, and melatonin.

As an added benefit, practitioners can select either an Adrenal Cortex Stress Profile Panel or Cortisol Awakening Response Panel to be run at no additional cost. If both are preferred, there will be an additional fee.

Learn more

The Choice is Yours. EndoSelect Salivary allows clinicians to order the salivary endocrine biomarkers designed for their patient’s unique needs, including:

  • Estradiol
  • Estriol*
  • Estrone*
  • Testosterone
  • Progesterone
  • DHEA
  • Cortisol 7AM-9AM
  • Cortisol 11AM-1PM
  • Cortisol 3PM-5PM
  • Cortisol 10PM-12AM
  • P/E2 Ratio and DHEA/Cortisol Ratio are included if the specific biomarkers are selected
Learn more

The Most Comprehensive Stool Test for Optimal Clinical Utility
The GI Effects® Comprehensive Stool Profile is an advanced stool test that provides immediate, actionable clinical information for the management of gastrointestinal health. Utilizing cutting-edge technologies and biomarkers, this test offers valuable insight into digestive function, intestinal inflammation, and the intestinal microbiome.

When Should the GI Effects Comprehensive Stool Profile Be Considered?
The GI Effects Comprehensive Stool Profile can reveal important information about the root cause of many common gastrointestinal symptoms such as gas, bloating, indigestion, abdominal pain, diarrhea, and constipation. This stool analysis utilizes biomarkers such as fecal calprotectin to differentiate between Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS). In addition, Genova’s GI Effects test can be used to evaluate patients with a clinical history that suggests a gastrointestinal infection or dysbiosis.

Gut microbes are codependent with one another and with their human host, and the health of one affects the other. A sizeable volume of research associates a dysbiotic, or imbalanced gut microbiome with multiple disease states both within and outside of the GI tract.2,3 The diverse metabolic activities of the microbiome ultimately impact the human host, and the activities of the human host ultimately affect the health of their microbiome.

Why Choose Genova Diagnostics’ Gastrointestinal Products?

  • GI Effects is a comprehensive assessment of complete GI health, assessing the root cause of most gut complaints.
  • Genova uses a combination of PCR, culture, and microscopic methods to ensure any and all relevant organisms are identified.
  • Genova recovers live organisms (yeast and bacteria) for susceptibility testing and improved treatment options.
  • Genova measures metabolomics and can assess the interaction between the microbiome and its host.
  • Genova is the market authority on stool inflammatory markers, testing calprotectin, EPX and sIgA.
  • Genova has amassed a database of hundreds of thousands of complete stool profiles. Our data driven and evidence-based analysis ensures the highest standard of analytical validity and clinical utility.
Learn More

The GI Effects Microbial Ecology Profile is Genova’s most comprehensive stool test that assesses the diverse gut microbiome. Results provide immediate, actionable clinical information for the management of detectable parasites, bacteria, and yeast, as well as providing valuable assessment of gut microbiota via 24 Commensal Bacteria targets.

The GI Effects Microbial Ecology Profile is part of the larger GI Effects Comprehensive Stool Profile, which also provides information about digestion, inflammation, and bacterial metabolism markers. A larger fecal biomarker panel such as the GI Effects Comprehensive Stool Profile offers the advantage of assessing multiple functional areas that may be contributing to symptoms. For example, diarrhea could stem from multiple causes including pancreatic exocrine insufficiency, inflammation, food allergies, or the presence of a pathogenic or potentially pathogenic organism.

Why Choose Genova Diagnostics’ Gastrointestinal Products?

  • GI Effects is a comprehensive assessment of complete GI health, assessing the root cause of most gut complaints.
  • Genova uses a combination of PCR, culture, and microscopic methods to ensure any and all relevant organisms are identified.
  • Genova recovers live organisms (yeast and bacteria) for susceptibility testing and improved treatment options.
  • Genova measures metabolomics and can assess the interaction between the microbiome and its host.
  • Genova is the market authority on stool inflammatory markers, testing calprotectin, EPX and sIgA.
  • Genova has amassed a database of hundreds of thousands of complete stool profiles. Our data driven and evidence-based analysis ensures the highest standard of analytical validity and clinical utility.
Learn More

A Targeted Stool Test for Optimal Clinical Utility

The Gut Pathogen Profile is a comprehensive stool assessment for pathogenic or potentially pathogenic organisms. Results provide immediate, actionable clinical information for the management of detectable parasites, bacteria, and yeast.

When Should the GI Effects Gut Pathogen Profile Be Considered?
Patients with a clinical history suggestive of a gastrointestinal infection or dysbiosis can be evaluated with the Gut Pathogen Profile. Testing is ideal for patients with sudden changes in bowel habits, especially for those who have recently traveled abroad, have been camping, had exposure to untreated water, had close contact with animals, or consumed undercooked meat or seafood. Symptoms such as gas, bloating, nausea, abdominal pain, anal itching, and diarrhea may be a result of a parasitic, bacterial, or fungal infection. This profile can also be used to assess efficacy of therapy.

Selection of a one-day or three-day sample collection is based on the clinician’s index of suspicion for parasitic infection. If there is no/low suspicion, a one-day sample will likely be adequate. For high suspicion, a three-day sample collection is optimal.

What Advantage Does the Gut Pathogen Profile Offer Compared to Other Diagnostics?
Genova uses a combination of PCR, culture, and microscopic methods to ensure identification of any and all relevant organisms. Utilizing a single technology cannot fully capture the dynamics of the microbiome. Genova offers the best technical platforms available to assess the gut microbiome, combining:

  • The 16S rRNA gene polymerase chain reaction (PCR) amplification technique for anaerobic commensal bacteria
  • Matrix Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) technology for bacterial and fungal species identification via culture
  • Gold standard microscopic ova & parasites (O&P) detection
  • Real-time PCR for the identification of 6 common parasites
  • Next-Generation DNA sequencing for Blastocystis spp. with reflex subtyping 1-9
Learn More

Comprehensive Stool Analysis for Optimal Clinical Utility

The Comprehensive Digestive Stool Analysis (CDSA)™ offers a comprehensive look at the overall health of the gastrointestinal (GI) tract. The CDSA™ is Genova’s historic evaluation of gastrointestinal function assessing a select set of stool biomarkers.

This stool analysis evaluates:

  • Digestion/Absorption Markers
  • Gut Metabolic Markers
  • Gut Microbiology Markers

This diagnostic stool analysis provides immediate, actionable clinical information for the estimated 50% of patients seen by primary care practitioners who have gastrointestinal complaints.

CDSA Stool Analysis offers insight into common gastrointestinal conditions
Evidence suggests that both local and systemic health issues may begin as imbalances in gastrointestinal function.

  • Maldigestion
  • Malabsorption
  • Irritable Bowel Syndrome (IBS)
  • Altered GI immune function
  • Bacterial/fungal overgrowth
  • Chronic dysbiosis
Learn More

Comprehensive Stool Analysis for Optimal Clinical Utility

The Comprehensive Digestive Stool Analysis (CDSA)™ with parasitology offers a comprehensive look at the overall health of the gastrointestinal (GI) tract. The (CDSA)™ is Genova’s historic evaluation of gastrointestinal function assessing a select set of stool biomarkers.

This stool analysis evaluates:

  • Digestion/Absorption Markers
  • Gut Microbiology Markers
  • Gut Metabolic Markers
  • Gold standard O&P (ova & parasite) technology as well as EIA (Enzyme Immunoassay) for identification of common parasites

CDSA/P™ Stool Analysis Offers Insight into Common Gastrointestinal Conditions
Evidence suggests that both local and systemic health issues may begin as imbalances in gastrointestinal function. Some of the consequences of imbalanced gastrointestinal health are:

  • Maldigestion
  • Malabsorption
  • Irritable Bowel Syndrome (IBS)
  • Altered GI immune function
  • Bacterial/fungal overgrowth
  • Chronic dysbiosis
Learn More

Comprehensive Stool Analysis for Optimal Clinical Utility

What is the Comprehensive Digestive Stool Analysis™ (CDSA 2.0)?

The Comprehensive Digestive Stool Analysis 2.0™ (CDSA 2.0) is an advanced stool test that provides immediate, actionable clinical information for the management of gastrointestinal health. Utilizing cutting-edge technologies and biomarkers, this test offers valuable insight into digestive function, intestinal inflammation, and the intestinal microbiome.

When should the CDSA 2.0 be considered?

The CDSA 2.0 Profile can reveal important information about the root cause of many common gastrointestinal symptoms such as gas, bloating, indigestion, abdominal pain, diarrhea, and constipation. This stool analysis utilizes biomarkers such as Calprotectin to differentiate between Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS).1,2 In addition, Genova’s CDSA 2.0 test can be used to evaluate patients with a clinical history that suggests a gastrointestinal infection or dysbiosis.

Learn More

CDSA 2.0™ without Parasitology Stool Analysis Offers Insight into Common Gastrointestinal Conditions

What is the Comprehensive Digestive Stool Analysis™ without Parasitology (CDSA 2.0)?
The Comprehensive Digestive Stool Analysis 2.0™ without Parasitology (CDSA 2.0) is an advanced stool test that provides immediate, actionable clinical information for the management of gastrointestinal health. Utilizing cutting-edge technologies and biomarkers, this test offers valuable insight into digestive function, intestinal inflammation, and the intestinal microbiome.

When should the CDSA 2.0 without Parasitology be considered?
The CDSA 2.0 without Parasitology Profile can reveal important information about the root cause of many common gastrointestinal symptoms such as gas, bloating, indigestion, abdominal pain, diarrhea, and constipation. This stool analysis utilizes biomarkers such as Calprotectin to differentiate between Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS). In addition, Genova’s CDSA 2.0 test can be used to evaluate patients with a clinical history that suggests a gastrointestinal infection or dysbiosis.

Learn More

Uncover the Cause of Unexplained Abdominal Symptoms with Breath Testing

SIBO is a common clinical condition and can develop in a variety of patient populations.
Genova’s SIBO Profiles are non-invasive breath tests which capture exhaled hydrogen (H2) and methane (CH4) gases following patient ingestion of a lactulose solution to evaluate bacterial overgrowth of the
small intestine.

Clinicians have the option of a 2 or 3-hour SIBO assessment
The 3-hour SIBO profile provides insight into gas levels over a longer period of time, and is recommended for patients with slower gastrointestinal transit or constipation.

When should testing for SIBO be considered?
Symptoms of SIBO are non-specific, encompassing abdominal pain/distention, diarrhea, and flatulence.

  • IBS
  • IBD
  • Celiac Disease
  • Diabetes
  • Fibromyalgia
  • Rosacea
  • Parkinson’s Disease
  • Obesity
Learn More

The Most Comprehensive Stool Test for Optimal Clinical Utility
The GI Effects® Comprehensive Stool Profile is an advanced stool test that provides immediate, actionable clinical information for the management of gastrointestinal health. Utilizing cutting-edge technologies and biomarkers, this test offers valuable insight into digestive function, intestinal inflammation, and the intestinal microbiome.

When Should the GI Effects Comprehensive Stool Profile Be Considered?
The GI Effects Comprehensive Stool Profile can reveal important information about the root cause of many common gastrointestinal symptoms such as gas, bloating, indigestion, abdominal pain, diarrhea, and constipation. This stool analysis utilizes biomarkers such as fecal calprotectin to differentiate between Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS). In addition, Genova’s GI Effects test can be used to evaluate patients with a clinical history that suggests a gastrointestinal infection or dysbiosis.

Gut microbes are codependent with one another and with their human host, and the health of one affects the other. A sizeable volume of research associates a dysbiotic, or imbalanced gut microbiome with multiple disease states both within and outside of the GI tract.2,3 The diverse metabolic activities of the microbiome ultimately impact the human host, and the activities of the human host ultimately affect the health of their microbiome.

Why Choose Genova Diagnostics’ Gastrointestinal Products?

  • GI Effects is a comprehensive assessment of complete GI health, assessing the root cause of most gut complaints.
  • Genova uses a combination of PCR, culture, and microscopic methods to ensure any and all relevant organisms are identified.
  • Genova recovers live organisms (yeast and bacteria) for susceptibility testing and improved treatment options.
  • Genova measures metabolomics and can assess the interaction between the microbiome and its host.
  • Genova is the market authority on stool inflammatory markers, testing calprotectin, EPX and sIgA.
  • Genova has amassed a database of hundreds of thousands of complete stool profiles. Our data driven and evidence-based analysis ensures the highest standard of analytical validity and clinical utility.
Learn More

The GI Effects Microbial Ecology Profile is Genova’s most comprehensive stool test that assesses the diverse gut microbiome. Results provide immediate, actionable clinical information for the management of detectable parasites, bacteria, and yeast, as well as providing valuable assessment of gut microbiota via 24 Commensal Bacteria targets.

The GI Effects Microbial Ecology Profile is part of the larger GI Effects Comprehensive Stool Profile, which also provides information about digestion, inflammation, and bacterial metabolism markers. A larger fecal biomarker panel such as the GI Effects Comprehensive Stool Profile offers the advantage of assessing multiple functional areas that may be contributing to symptoms. For example, diarrhea could stem from multiple causes including pancreatic exocrine insufficiency, inflammation, food allergies, or the presence of a pathogenic or potentially pathogenic organism.

Why Choose Genova Diagnostics’ Gastrointestinal Products?

  • GI Effects is a comprehensive assessment of complete GI health, assessing the root cause of most gut complaints.
  • Genova uses a combination of PCR, culture, and microscopic methods to ensure any and all relevant organisms are identified.
  • Genova recovers live organisms (yeast and bacteria) for susceptibility testing and improved treatment options.
  • Genova measures metabolomics and can assess the interaction between the microbiome and its host.
  • Genova is the market authority on stool inflammatory markers, testing calprotectin, EPX and sIgA.
  • Genova has amassed a database of hundreds of thousands of complete stool profiles. Our data driven and evidence-based analysis ensures the highest standard of analytical validity and clinical utility.
Learn More

A Targeted Stool Test for Optimal Clinical Utility

The Gut Pathogen Profile is a comprehensive stool assessment for pathogenic or potentially pathogenic organisms. Results provide immediate, actionable clinical information for the management of detectable parasites, bacteria, and yeast.

When Should the GI Effects Gut Pathogen Profile Be Considered?
Patients with a clinical history suggestive of a gastrointestinal infection or dysbiosis can be evaluated with the Gut Pathogen Profile. Testing is ideal for patients with sudden changes in bowel habits, especially for those who have recently traveled abroad, have been camping, had exposure to untreated water, had close contact with animals, or consumed undercooked meat or seafood. Symptoms such as gas, bloating, nausea, abdominal pain, anal itching, and diarrhea may be a result of a parasitic, bacterial, or fungal infection. This profile can also be used to assess efficacy of therapy.

Selection of a one-day or three-day sample collection is based on the clinician’s index of suspicion for parasitic infection. If there is no/low suspicion, a one-day sample will likely be adequate. For high suspicion, a three-day sample collection is optimal.

What Advantage Does the Gut Pathogen Profile Offer Compared to Other Diagnostics?
Genova uses a combination of PCR, culture, and microscopic methods to ensure identification of any and all relevant organisms. Utilizing a single technology cannot fully capture the dynamics of the microbiome. Genova offers the best technical platforms available to assess the gut microbiome, combining:

  • The 16S rRNA gene polymerase chain reaction (PCR) amplification technique for anaerobic commensal bacteria
  • Matrix Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) technology for bacterial and fungal species identification via culture
  • Gold standard microscopic ova & parasites (O&P) detection
  • Real-time PCR for the identification of 6 common parasites
  • Next-Generation DNA sequencing for Blastocystis spp. with reflex subtyping 1-9
Learn More

Comprehensive Stool Analysis for Optimal Clinical Utility

The Comprehensive Digestive Stool Analysis (CDSA)™ offers a comprehensive look at the overall health of the gastrointestinal (GI) tract. The CDSA™ is Genova’s historic evaluation of gastrointestinal function assessing a select set of stool biomarkers.

This stool analysis evaluates:

  • Digestion/Absorption Markers
  • Gut Metabolic Markers
  • Gut Microbiology Markers

This diagnostic stool analysis provides immediate, actionable clinical information for the estimated 50% of patients seen by primary care practitioners who have gastrointestinal complaints.

CDSA Stool Analysis offers insight into common gastrointestinal conditions
Evidence suggests that both local and systemic health issues may begin as imbalances in gastrointestinal function.

  • Maldigestion
  • Malabsorption
  • Irritable Bowel Syndrome (IBS)
  • Altered GI immune function
  • Bacterial/fungal overgrowth
  • Chronic dysbiosis
Learn More

Comprehensive Stool Analysis for Optimal Clinical Utility

The Comprehensive Digestive Stool Analysis (CDSA)™ with parasitology offers a comprehensive look at the overall health of the gastrointestinal (GI) tract. The (CDSA)™ is Genova’s historic evaluation of gastrointestinal function assessing a select set of stool biomarkers.

This stool analysis evaluates:

  • Digestion/Absorption Markers
  • Gut Microbiology Markers
  • Gut Metabolic Markers
  • Gold standard O&P (ova & parasite) technology as well as EIA (Enzyme Immunoassay) for identification of common parasites

CDSA/P™ Stool Analysis Offers Insight into Common Gastrointestinal Conditions
Evidence suggests that both local and systemic health issues may begin as imbalances in gastrointestinal function. Some of the consequences of imbalanced gastrointestinal health are:

  • Maldigestion
  • Malabsorption
  • Irritable Bowel Syndrome (IBS)
  • Altered GI immune function
  • Bacterial/fungal overgrowth
  • Chronic dysbiosis
Learn More

Comprehensive Stool Analysis for Optimal Clinical Utility

What is the Comprehensive Digestive Stool Analysis™ (CDSA 2.0)?

The Comprehensive Digestive Stool Analysis 2.0™ (CDSA 2.0) is an advanced stool test that provides immediate, actionable clinical information for the management of gastrointestinal health. Utilizing cutting-edge technologies and biomarkers, this test offers valuable insight into digestive function, intestinal inflammation, and the intestinal microbiome.

When should the CDSA 2.0 be considered?

The CDSA 2.0 Profile can reveal important information about the root cause of many common gastrointestinal symptoms such as gas, bloating, indigestion, abdominal pain, diarrhea, and constipation. This stool analysis utilizes biomarkers such as Calprotectin to differentiate between Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS).1,2 In addition, Genova’s CDSA 2.0 test can be used to evaluate patients with a clinical history that suggests a gastrointestinal infection or dysbiosis.

Learn More

CDSA 2.0™ without Parasitology Stool Analysis Offers Insight into Common Gastrointestinal Conditions

What is the Comprehensive Digestive Stool Analysis™ without Parasitology (CDSA 2.0)?
The Comprehensive Digestive Stool Analysis 2.0™ without Parasitology (CDSA 2.0) is an advanced stool test that provides immediate, actionable clinical information for the management of gastrointestinal health. Utilizing cutting-edge technologies and biomarkers, this test offers valuable insight into digestive function, intestinal inflammation, and the intestinal microbiome.

When should the CDSA 2.0 without Parasitology be considered?
The CDSA 2.0 without Parasitology Profile can reveal important information about the root cause of many common gastrointestinal symptoms such as gas, bloating, indigestion, abdominal pain, diarrhea, and constipation. This stool analysis utilizes biomarkers such as Calprotectin to differentiate between Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS). In addition, Genova’s CDSA 2.0 test can be used to evaluate patients with a clinical history that suggests a gastrointestinal infection or dysbiosis.

Learn More

Uncover the Cause of Unexplained Abdominal Symptoms with Breath Testing

SIBO is a common clinical condition and can develop in a variety of patient populations.
Genova’s SIBO Profiles are non-invasive breath tests which capture exhaled hydrogen (H2) and methane (CH4) gases following patient ingestion of a lactulose solution to evaluate bacterial overgrowth of the
small intestine.

Clinicians have the option of a 2 or 3-hour SIBO assessment
The 3-hour SIBO profile provides insight into gas levels over a longer period of time, and is recommended for patients with slower gastrointestinal transit or constipation.

When should testing for SIBO be considered?
Symptoms of SIBO are non-specific, encompassing abdominal pain/distention, diarrhea, and flatulence.

  • IBS
  • IBD
  • Celiac Disease
  • Diabetes
  • Fibromyalgia
  • Rosacea
  • Parkinson’s Disease
  • Obesity
Learn More

Complete Evaluation of Key Biomarkers of Metabolism

The Metabolic Analysis Profile is a nutrition test that requires a first morning void (FMV) urine collection to measure organic acids. The report includes personalized micronutrient recommendations for vitamin and mineral cofactors as well as digestive support recommendations based on a patient’s individual biochemical metabolism.

What is an organic acid?
Organic acids are a broad class of compounds formed during fundamental metabolic processes in the body. Metabolic reactions produce these compounds from the digestion of dietary protein, fat, and carbohydrates. The resulting organic acids are used by the body to generate cellular energy and provide many of the building blocks necessary for cell function. Urinary organic acid measurement offers a functional assessment of nutrient status.

Metabolic Analysis Profile testing is effective for patient concerns such as:

  • Mood Disorders
  • Mitochondrial Dysfunction
  • Fatigue
  • Chronic Stress
  • Inflammation
Learn More

Add-on options include BloodSpot Fatty Acids, Toxic Clearance Profile, or Comprehensive Urine Elements.

A Non-Invasive Personalized Assessment
Metabolomix+ is a urinary nutritional evaluation that includes key organic acids and amino acids to evaluate the functional need for antioxidants, B-vitamins, minerals, digestive support, and amino acids.

Can Assist Evaluation of:

  • Fatigue
  • Mood Disorders
  • Health Optimization/Dietary Guidance
  • Athletic Performance
  • Weight Issues
  • Digestive Complaints
Learn More

A Nutritional Assay for Personalized Supplementation

Featuring First Morning Void (FMV) Urine Amino Acids

Why Use the Amino Acid Analysis, FMV Profile?
The Amino Acid Analysis, FMV is a nutritional test that evaluates amino acids for advanced insight and targeted
treatment. Amino acid metabolism may be compromised by common lifestyle and dietary factors, which may result in inadequate levels of amino acids. Urine amino acid testing is specifically valuable for assessing vitamin/mineral cofactors that affect amino acid metabolism and provide insight into protein digestion.

Effective for Patients Experiencing
Clinical indications for testing include:

  • Increase the number of foreign compounds entering the bloodstream
    Allow bacterial antigens capable of cross-reacting with host tissue to enter the bloodstream, leading to auto-immune processes
  • Enhance the uptake of toxic compounds that can overwhelm the hepatic detoxification system and lead to an overly sensitized immune system
Learn More

The Toxic Element Clearance Profile offers an advanced, comprehensive assessment of toxic and potentially toxic elements excreted in the urine. In addition to measuring classic elemental toxins, such as lead and mercury, this profile includes elements used in medical, aerospace, nuclear, and high-tech electronic industries. Use of these potential toxins is increasing because of their growing commercial, industrial, and medical applications. Evidence suggests that chronic toxic element exposure can adversely affect:

  • Energy levels
  • Reproductive function
  • Cancer risk
  • Neurological development and function
  • Respiratory, cardiac, hepatic, and immune functions
  • Cognitive and emotional health
  • Degenerative conditions
Learn more

The Comprehensive Urine Elements Profile is Genova’s toxic exposure test which measures urinary excretion of 15 nutrient elements and 20 toxic metals.

Learn More

The Essential & Metabolic Fatty Acids Analysis (EMFA) assesses the critical balance between essential Omega-6/Omega-3 fatty acids, as well as additional key fatty acids important in metabolism and cellular function. Fatty acid imbalances can be a causative factor in a variety of chronic health conditions. The Essential and Metabolic Fatty Acids Analysis can indicate the need for fatty acid supplementation and/or dietary modification.

Effective for Patients Experiencing:

Essential and Metabolic Fatty Acids Analysis is useful for patient concerns including:

  • Chronic Pain/Inflammatory Conditions
  • Depression
  • Cardiovascular Risk
  • Weight Issues/Dietary Guidance
Learn More

Elemental Analysis evaluates patients for recent toxic element exposure and assesses nutrient mineral status. This assessment allows clinicians to provide targeted treatment for patients by identifying and correcting toxic-element exposures and replenishing nutrient minerals.

Effective for Patients Experiencing:

Research suggests that nutritional shortfalls or toxic exposure may be at the root of many chronic conditions. Patients that can benefit from Elemental Analysis testing may experience symptoms, such as:

  • Mood Disorders
    • Depression
    • Anxiety
  • Fatigue
  • Chronic Pain/Inflammatory Conditions
    • Musculoskeletal
    • Migraine
Learn More

The Methylation Panel is an innovative test designed to offer insight into the critical biochemical methylation pathway. Methylation metabolites are measured in plasma, and genetic single nucleotide polymorphisms (SNPs) are analyzed via buccal swab. The results are synthesized on a front-page Interpretation-at-a-Glance (IAAG) graphic for quick methylation status assessment. Within the report, results are shown in a methylation pathway graphic to provide a clear understanding of the biochemistry involved.

Which patients can benefit from the Methylation Panel?

Because of its all-encompassing role in basic human physiology, the range of symptoms associated with methylation defects is broad. The Methylation Panel can offer insight in patients with:

  • questionable detoxification (patients who take hormone therapy, drink alcohol, or have toxin exposure)
  • cancer risk
  • cardiovascular disease (non-coronary atherosclerosis, hypertension, coronary artery disease)
  • psychiatric and mood disorders (schizophrenia, bipolar disorder, anxiety, depression)
  • neurologic disorders (Parkinson’s disease, cognitive decline)
  • chronic fatigue
Learn more

The Amino Acid Analysis, Plasma measures levels of key amino acids in blood. Amino acid metabolism may be compromised by common lifestyle and dietary factors, which may result in inadequate levels of amino acids. Plasma amino acid analysis is favored in conditions where the supply of amino acids and precursors is critical, such as in mood and neurobehavioral disorders.

The complete Amino Acid Analysis, Plasma analyzes over 30 analytes, and includes:

  • Nutritionally Essential Amino Acids
  • Nonessential Protein Amino Acids
  • Intermediary Metabolites
  • Dietary Peptide Related Markers

Effective for patients experiencing:

  • Dietary Issues Related to Protein Intake and Digestion
  • Weight Issues/Dietary Guidance
  • Mood Disorders
Learn More

The NutrEval FMV® is both a blood and urine test that evaluates over 125 biomarkers and assesses the body’s functional need for 40 antioxidants, vitamins, minerals, essential fatty acids, amino acids, digestive support, and other select nutrients. Personalized recommendations for nutrients are determined by using an algorithm based on the patient’s test findings. The NutrEval Plasma and NutrEval FMV (first morning void) differ based on which sample type is used to measure amino acids, plasma or urine.

According to the World Health Organization, every country in the world is affected by one or more forms of malnutrition. The term malnutrition addresses 3 broad groups of conditions:1

  • Undernutrition (wasting, stunting, underweight)
  • Micronutrient-related malnutrition from inadequate or excess vitamins or minerals
  • Overweight, obesity, and diet-related noncommunicable diseases (such as heart disease, stroke, diabetes and some cancers)

Symptoms and conditions associated with nutrient imbalances

  • Mood disorders
  • Cardiovascular disease
  • Obesity/ Insulin resistance/ Type 2 Diabetes
  • Autism
  • Fatigue
  • Weight Issues/ Malnutrition/ Dietary Guidance
  • Maldigestion/Malabsorption
  • Increased nutrient demand in physical trauma/healing
Learn More

The NutrEval Plasma® is both a blood and urine test that evaluates over 125 biomarkers and assesses the body’s functional need for 40 antioxidants, vitamins, minerals, essential fatty acids, amino acids, digestive support, and other select nutrients. Personalized recommendations for nutrients are determined by using an algorithm based on the patient’s test findings. The NutrEval Plasma and NutrEval FMV (first morning void) differ based on which sample type is used to measure amino acids, plasma or urine.

According to the World Health Organization, every country in the world is affected by one or more forms of malnutrition. The term malnutrition addresses 3 broad groups of conditions:

  • Undernutrition (wasting, stunting, underweight)
  • Micronutrient-related malnutrition from inadequate or excess vitamins or minerals
  • Overweight, obesity, and diet-related noncommunicable diseases (such as heart disease, stroke, diabetes and some cancers)

Symptoms and conditions associated with nutrient imbalances

  • Mood disorders
  • Cardiovascular disease
  • Obesity/ Insulin resistance/ Type 2 Diabetes
  • Fatigue
  • Weight Issues / Dietary Guidance
  • Malnutrition often observed in the elderly
  • Maldigestion/Malabsorption
  • Increased nutrient demand in athletes
  • Increased nutrient demand in physical trauma/healing
Learn More

The ION Profile is a nutritional analysis that measures over 125 key nutrient biomarkers and ratios that can help identify nutritional shortfalls that may be a root cause of complex chronic conditions. The ION Profile evaluates organic acids, fat-soluble vitamins, Coenzyme Q10, homocysteine, oxidative stress markers, nutrient and toxic elements, fatty acids, and amino acids.

Nutritional analysis using the ION Profile allows for personalized treatment plans to improve nutritional status, which can enhance other treatments and increase the resolution of complex chronic conditions.

Over time, functional nutritional inadequacies can contribute to a variety of chronic health conditions. Clinical indications for testing include:

  • Mood Disorders
    • Depression
    • Anxiety
  • Fatigue
  • Digestive Complaints
  • Chronic Pain/Inflammatory Conditions
    • Musculoskeletal
    • Migraine
  • Cardiovascular Risk
  • Weight Issues/Dietary Guidance
  • General Health and Sports Fitness Optimization
Learn More

The ION® (Individual Optimal Nutrition) Profile with 40 Amino Acids nutritional analysis can help identify nutrient deficiencies that may be a root cause of complex chronic conditions. The ION with 40 Amino Acids is ideal for establishing a baseline assessment ahead of clinical intervention with nutraceuticals as well as subsequent monitoring as needed.

By evaluating 150 key biomarkers and ratios, the ION Profile with 40 Amino Acids evaluates organic acids, fat-soluble vitamins, Coenzyme Q10, homocysteine, oxidative stress markers, nutrient and toxic elements, fatty acids, and amino acids.

The ION Profile with 40 Amino Acids provides an expanded amino acid panel for enhanced clinical insight. Results can be used to personalize treatment plans to improve nutritional status, augment other treatments, and increase the resolution of complex chronic conditions.

Over time, functional nutritional inadequacies can contribute to a variety of chronic health conditions. Clinical indications for testing include:

  • Mood Disorders
    • Depression
    • Anxiety
  • Fatigue
  • Digestive Complaints
  • Chronic Pain/Inflammatory Conditions
    • Musculoskeletal
    • Migraine
  • Cardiovascular Risk
  • Weight Issues/Dietary Guidance
  • General Health and Sports Fitness Optimization
Learn More

The Organix® Comprehensive Profile is a nutritional test providing insights into organic acids and a view into the body’s cellular metabolic processes. Additionally, children’s reference ranges are designed to provide more accurate pediatric nutritional evaluations. Identifying metabolic blocks that can be treated nutritionally allows individual tailoring of interventions that maximize patient responses and lead to improved patient outcomes.

The Organix® Comprehensive nutritional test profile provides vital patient information from a single urine specimen. This organic acids nutritional test is valuable for determining:

  • Functional vitamin and mineral status
  • Amino acid insufficiencies like carnitine and NAC
  • Oxidative damage and antioxidant need
  • Phase I & Phase II detoxification capacity
  • Functional B-complex vitamin need
  • Neurotransmitter metabolites
  • Mitochondrial energy production
  • Methylation sufficiency
  • Lipoic acid and CoQ10 status
  • Markers for bacterial and yeast overgrowth

The Organix® Comprehensive nutritional test is ideal for patients who may suffer from:

  • Weight issues
  • Sleep abnormalities
  • Depression
  • Chemical Sensitivities
Learn More

The Organix® Dysbiosis Profile is a urine organic acid test measuring the by-products of microbial metabolism, and is particularly useful in detecting the presence of pathogenic microbial overgrowth. As a stand-alone test, the Organix® Dysbiosis Profile is a great follow-up option to the Organix® Comprehensive Profile, allowing the clinician to assess microbial overgrowth and guide and monitor targeted therapy in patients.

Symptoms of dysbiosis can be as diverse as:

  • Behavioral disorders
  • Chronic fatigue
  • Depression
  • Headache
  • Immune dysfunction
  • Insomnia
  • Irritable Bowel Syndrome (IBS)
  • Joint pain
  • Learning disorders
  • Nutritional deficiencies
  • Food allergies
  • Skin disorders, acne
Learn More

Organic acids are metabolic intermediates produced in pathways of central energy production, detoxification, neurotransmitter breakdown, and intestinal microbial activity. Accumulation of specific organic acids in urine often signals a metabolic inhibition or block. This abnormality may be due to a nutrient deficiency, an inherited enzyme deficit, toxic build-up, or drug effect. An organic acids urine test helps reveal activity and changes at the metabolic level, helping practitioners discover hidden issues and pinpoint where therapeutic focus is needed.

Advantages of the Organix Basic Profile (without dysbiosis markers):

  • Innovative Method – The LC/MS-MS method, which is also used to screen newborns for metabolic disorders, requires very little sample preparation and processing. This technology provides more stability, accuracy, and sensitivity in measuring organic acids at low levels for optimum test results.
  • Single Urine Specimen – A single overnight urine collection is easy for patients, leading to increased patient compliance.
  • Follow-up Testing Option – The Organix Basic offers an easy and affordable follow-up testing option to monitor targeted therapy in patients when dysbiosis markers are unneeded.
Learn More

Complete Evaluation of Key Biomarkers of Metabolism

The Metabolic Analysis Profile is a nutrition test that requires a first morning void (FMV) urine collection to measure organic acids. The report includes personalized micronutrient recommendations for vitamin and mineral cofactors as well as digestive support recommendations based on a patient’s individual biochemical metabolism.

What is an organic acid?
Organic acids are a broad class of compounds formed during fundamental metabolic processes in the body. Metabolic reactions produce these compounds from the digestion of dietary protein, fat, and carbohydrates. The resulting organic acids are used by the body to generate cellular energy and provide many of the building blocks necessary for cell function. Urinary organic acid measurement offers a functional assessment of nutrient status.

Metabolic Analysis Profile testing is effective for patient concerns such as:

  • Mood Disorders
  • Mitochondrial Dysfunction
  • Fatigue
  • Chronic Stress
  • Inflammation
Learn More

Add-on options include BloodSpot Fatty Acids, Toxic Clearance Profile, or Comprehensive Urine Elements.

A Non-Invasive Personalized Assessment
Metabolomix+ is a urinary nutritional evaluation that includes key organic acids and amino acids to evaluate the functional need for antioxidants, B-vitamins, minerals, digestive support, and amino acids.

Can Assist Evaluation of:

  • Fatigue
  • Mood Disorders
  • Health Optimization/Dietary Guidance
  • Athletic Performance
  • Weight Issues
  • Digestive Complaints
Learn More

A Nutritional Assay for Personalized Supplementation

Featuring First Morning Void (FMV) Urine Amino Acids

Why Use the Amino Acid Analysis, FMV Profile?
The Amino Acid Analysis, FMV is a nutritional test that evaluates amino acids for advanced insight and targeted
treatment. Amino acid metabolism may be compromised by common lifestyle and dietary factors, which may result in inadequate levels of amino acids. Urine amino acid testing is specifically valuable for assessing vitamin/mineral cofactors that affect amino acid metabolism and provide insight into protein digestion.

Effective for Patients Experiencing
Clinical indications for testing include:

  • Increase the number of foreign compounds entering the bloodstream
    Allow bacterial antigens capable of cross-reacting with host tissue to enter the bloodstream, leading to auto-immune processes
  • Enhance the uptake of toxic compounds that can overwhelm the hepatic detoxification system and lead to an overly sensitized immune system
Learn More

The Toxic Element Clearance Profile offers an advanced, comprehensive assessment of toxic and potentially toxic elements excreted in the urine. In addition to measuring classic elemental toxins, such as lead and mercury, this profile includes elements used in medical, aerospace, nuclear, and high-tech electronic industries. Use of these potential toxins is increasing because of their growing commercial, industrial, and medical applications. Evidence suggests that chronic toxic element exposure can adversely affect:

  • Energy levels
  • Reproductive function
  • Cancer risk
  • Neurological development and function
  • Respiratory, cardiac, hepatic, and immune functions
  • Cognitive and emotional health
  • Degenerative conditions
Learn more

The Comprehensive Urine Elements Profile is Genova’s toxic exposure test which measures urinary excretion of 15 nutrient elements and 20 toxic metals.

Learn More

The Essential & Metabolic Fatty Acids Analysis (EMFA) assesses the critical balance between essential Omega-6/Omega-3 fatty acids, as well as additional key fatty acids important in metabolism and cellular function. Fatty acid imbalances can be a causative factor in a variety of chronic health conditions. The Essential and Metabolic Fatty Acids Analysis can indicate the need for fatty acid supplementation and/or dietary modification.

Effective for Patients Experiencing:

Essential and Metabolic Fatty Acids Analysis is useful for patient concerns including:

  • Chronic Pain/Inflammatory Conditions
  • Depression
  • Cardiovascular Risk
  • Weight Issues/Dietary Guidance
Learn More

Elemental Analysis evaluates patients for recent toxic element exposure and assesses nutrient mineral status. This assessment allows clinicians to provide targeted treatment for patients by identifying and correcting toxic-element exposures and replenishing nutrient minerals.

Effective for Patients Experiencing:

Research suggests that nutritional shortfalls or toxic exposure may be at the root of many chronic conditions. Patients that can benefit from Elemental Analysis testing may experience symptoms, such as:

  • Mood Disorders
    • Depression
    • Anxiety
  • Fatigue
  • Chronic Pain/Inflammatory Conditions
    • Musculoskeletal
    • Migraine
Learn More

The Methylation Panel is an innovative test designed to offer insight into the critical biochemical methylation pathway. Methylation metabolites are measured in plasma, and genetic single nucleotide polymorphisms (SNPs) are analyzed via buccal swab. The results are synthesized on a front-page Interpretation-at-a-Glance (IAAG) graphic for quick methylation status assessment. Within the report, results are shown in a methylation pathway graphic to provide a clear understanding of the biochemistry involved.

Which patients can benefit from the Methylation Panel?

Because of its all-encompassing role in basic human physiology, the range of symptoms associated with methylation defects is broad. The Methylation Panel can offer insight in patients with:

  • questionable detoxification (patients who take hormone therapy, drink alcohol, or have toxin exposure)
  • cancer risk
  • cardiovascular disease (non-coronary atherosclerosis, hypertension, coronary artery disease)
  • psychiatric and mood disorders (schizophrenia, bipolar disorder, anxiety, depression)
  • neurologic disorders (Parkinson’s disease, cognitive decline)
  • chronic fatigue
Learn more

The Amino Acid Analysis, Plasma measures levels of key amino acids in blood. Amino acid metabolism may be compromised by common lifestyle and dietary factors, which may result in inadequate levels of amino acids. Plasma amino acid analysis is favored in conditions where the supply of amino acids and precursors is critical, such as in mood and neurobehavioral disorders.

The complete Amino Acid Analysis, Plasma analyzes over 30 analytes, and includes:

  • Nutritionally Essential Amino Acids
  • Nonessential Protein Amino Acids
  • Intermediary Metabolites
  • Dietary Peptide Related Markers

Effective for patients experiencing:

  • Dietary Issues Related to Protein Intake and Digestion
  • Weight Issues/Dietary Guidance
  • Mood Disorders
Learn More

The NutrEval FMV® is both a blood and urine test that evaluates over 125 biomarkers and assesses the body’s functional need for 40 antioxidants, vitamins, minerals, essential fatty acids, amino acids, digestive support, and other select nutrients. Personalized recommendations for nutrients are determined by using an algorithm based on the patient’s test findings. The NutrEval Plasma and NutrEval FMV (first morning void) differ based on which sample type is used to measure amino acids, plasma or urine.

According to the World Health Organization, every country in the world is affected by one or more forms of malnutrition. The term malnutrition addresses 3 broad groups of conditions:1

  • Undernutrition (wasting, stunting, underweight)
  • Micronutrient-related malnutrition from inadequate or excess vitamins or minerals
  • Overweight, obesity, and diet-related noncommunicable diseases (such as heart disease, stroke, diabetes and some cancers)

Symptoms and conditions associated with nutrient imbalances

  • Mood disorders
  • Cardiovascular disease
  • Obesity/ Insulin resistance/ Type 2 Diabetes
  • Autism
  • Fatigue
  • Weight Issues/ Malnutrition/ Dietary Guidance
  • Maldigestion/Malabsorption
  • Increased nutrient demand in physical trauma/healing
Learn More

The NutrEval Plasma® is both a blood and urine test that evaluates over 125 biomarkers and assesses the body’s functional need for 40 antioxidants, vitamins, minerals, essential fatty acids, amino acids, digestive support, and other select nutrients. Personalized recommendations for nutrients are determined by using an algorithm based on the patient’s test findings. The NutrEval Plasma and NutrEval FMV (first morning void) differ based on which sample type is used to measure amino acids, plasma or urine.

According to the World Health Organization, every country in the world is affected by one or more forms of malnutrition. The term malnutrition addresses 3 broad groups of conditions:

  • Undernutrition (wasting, stunting, underweight)
  • Micronutrient-related malnutrition from inadequate or excess vitamins or minerals
  • Overweight, obesity, and diet-related noncommunicable diseases (such as heart disease, stroke, diabetes and some cancers)

Symptoms and conditions associated with nutrient imbalances

  • Mood disorders
  • Cardiovascular disease
  • Obesity/ Insulin resistance/ Type 2 Diabetes
  • Fatigue
  • Weight Issues / Dietary Guidance
  • Malnutrition often observed in the elderly
  • Maldigestion/Malabsorption
  • Increased nutrient demand in athletes
  • Increased nutrient demand in physical trauma/healing
Learn More

The ION Profile is a nutritional analysis that measures over 125 key nutrient biomarkers and ratios that can help identify nutritional shortfalls that may be a root cause of complex chronic conditions. The ION Profile evaluates organic acids, fat-soluble vitamins, Coenzyme Q10, homocysteine, oxidative stress markers, nutrient and toxic elements, fatty acids, and amino acids.

Nutritional analysis using the ION Profile allows for personalized treatment plans to improve nutritional status, which can enhance other treatments and increase the resolution of complex chronic conditions.

Over time, functional nutritional inadequacies can contribute to a variety of chronic health conditions. Clinical indications for testing include:

  • Mood Disorders
    • Depression
    • Anxiety
  • Fatigue
  • Digestive Complaints
  • Chronic Pain/Inflammatory Conditions
    • Musculoskeletal
    • Migraine
  • Cardiovascular Risk
  • Weight Issues/Dietary Guidance
  • General Health and Sports Fitness Optimization
Learn More

The ION® (Individual Optimal Nutrition) Profile with 40 Amino Acids nutritional analysis can help identify nutrient deficiencies that may be a root cause of complex chronic conditions. The ION with 40 Amino Acids is ideal for establishing a baseline assessment ahead of clinical intervention with nutraceuticals as well as subsequent monitoring as needed.

By evaluating 150 key biomarkers and ratios, the ION Profile with 40 Amino Acids evaluates organic acids, fat-soluble vitamins, Coenzyme Q10, homocysteine, oxidative stress markers, nutrient and toxic elements, fatty acids, and amino acids.

The ION Profile with 40 Amino Acids provides an expanded amino acid panel for enhanced clinical insight. Results can be used to personalize treatment plans to improve nutritional status, augment other treatments, and increase the resolution of complex chronic conditions.

Over time, functional nutritional inadequacies can contribute to a variety of chronic health conditions. Clinical indications for testing include:

  • Mood Disorders
    • Depression
    • Anxiety
  • Fatigue
  • Digestive Complaints
  • Chronic Pain/Inflammatory Conditions
    • Musculoskeletal
    • Migraine
  • Cardiovascular Risk
  • Weight Issues/Dietary Guidance
  • General Health and Sports Fitness Optimization
Learn More

The Organix® Comprehensive Profile is a nutritional test providing insights into organic acids and a view into the body’s cellular metabolic processes. Additionally, children’s reference ranges are designed to provide more accurate pediatric nutritional evaluations. Identifying metabolic blocks that can be treated nutritionally allows individual tailoring of interventions that maximize patient responses and lead to improved patient outcomes.

The Organix® Comprehensive nutritional test profile provides vital patient information from a single urine specimen. This organic acids nutritional test is valuable for determining:

  • Functional vitamin and mineral status
  • Amino acid insufficiencies like carnitine and NAC
  • Oxidative damage and antioxidant need
  • Phase I & Phase II detoxification capacity
  • Functional B-complex vitamin need
  • Neurotransmitter metabolites
  • Mitochondrial energy production
  • Methylation sufficiency
  • Lipoic acid and CoQ10 status
  • Markers for bacterial and yeast overgrowth

The Organix® Comprehensive nutritional test is ideal for patients who may suffer from:

  • Weight issues
  • Sleep abnormalities
  • Depression
  • Chemical Sensitivities
Learn More

The Organix® Dysbiosis Profile is a urine organic acid test measuring the by-products of microbial metabolism, and is particularly useful in detecting the presence of pathogenic microbial overgrowth. As a stand-alone test, the Organix® Dysbiosis Profile is a great follow-up option to the Organix® Comprehensive Profile, allowing the clinician to assess microbial overgrowth and guide and monitor targeted therapy in patients.

Symptoms of dysbiosis can be as diverse as:

  • Behavioral disorders
  • Chronic fatigue
  • Depression
  • Headache
  • Immune dysfunction
  • Insomnia
  • Irritable Bowel Syndrome (IBS)
  • Joint pain
  • Learning disorders
  • Nutritional deficiencies
  • Food allergies
  • Skin disorders, acne
Learn More

Organic acids are metabolic intermediates produced in pathways of central energy production, detoxification, neurotransmitter breakdown, and intestinal microbial activity. Accumulation of specific organic acids in urine often signals a metabolic inhibition or block. This abnormality may be due to a nutrient deficiency, an inherited enzyme deficit, toxic build-up, or drug effect. An organic acids urine test helps reveal activity and changes at the metabolic level, helping practitioners discover hidden issues and pinpoint where therapeutic focus is needed.

Advantages of the Organix Basic Profile (without dysbiosis markers):

  • Innovative Method – The LC/MS-MS method, which is also used to screen newborns for metabolic disorders, requires very little sample preparation and processing. This technology provides more stability, accuracy, and sensitivity in measuring organic acids at low levels for optimum test results.
  • Single Urine Specimen – A single overnight urine collection is easy for patients, leading to increased patient compliance.
  • Follow-up Testing Option – The Organix Basic offers an easy and affordable follow-up testing option to monitor targeted therapy in patients when dysbiosis markers are unneeded.
Learn More

The IgE Food Antibody Assessment is a blood test that measures IgE antibodies to 19 of the most allergenic foods. The panel also includes a total IgE measurement. The body can react to foods in many different ways. The prevalence of food allergies in Western countries is rising, with up to 10% of the population affected. This trend likely involves a complex interplay between genetic, epigenetic, and environmental risk factors.

Conditions associated with IgE Food Allergy

  • Hives or red, itchy skin
  • Stuffy or itchy nose, sneezing or itchy, teary eyes
  • Vomiting, stomach cramps or diarrhea
  • Angioedema or swelling
  • Shortness of breath or wheezing
  • Anaphylaxis
Learn More

The IgE Inhalants Profile is a blood test that measures IgE antibodies to 16 common indoor and outdoor inhalants specific to 18 North American geographic regions. The profile also includes a total IgE measurement. Testing can help identify whether an allergen is triggering the common symptoms associated with seasonal, pet or mite allergies. These symptoms include sneezing, coughing, itchy and watery eyes, and others. The patient can experience relief with symptom management, and by avoiding ongoing exposure to the identified allergen.

Symptoms and conditions associated with IgE inhalant allergies

  • Stuffy or itchy nose, sneezing, rhinitis or sinusitis
  • Itchy, teary eyes, conjunctivitis
  • Cough, shortness of breath, wheezing, asthma
  • Skin rash or hives
Learn More

The IgE Mold Profile is a blood test that measures IgE antibodies to 15 common indoor and outdoor molds. The panel also includes a total IgE measurement. Everyone breathes in airborne mold spores, and in people with mold allergies, symptoms mainly affect the respiratory tract. Testing for mold allergies can identify whether mold is causing the symptoms. The patient can experience relief with symptom management, and by avoiding ongoing exposure to the mold source.

Symptoms and conditions associated with IgE mold allergies

  • Stuffy or itchy nose, sneezing, rhinitis or sinusitis
  • Itchy, teary eyes, conjunctivitis
  • Cough, shortness of breath, wheezing, asthma
  • Skin rash or hives

Occupations at greater risk of developing a mold allergy

  • Farmers
  • Dairyworkers
  • Loggers
  • Bakers
  • Mill workers
  • Carpenters
  • Greenhouse employees
  • Winemakers
  • Furniture repairers
Learn More

The IgE Food Antibody Assessment is a blood test that measures IgE antibodies to 19 of the most allergenic foods. The panel also includes a total IgE measurement. The body can react to foods in many different ways. The prevalence of food allergies in Western countries is rising, with up to 10% of the population affected. This trend likely involves a complex interplay between genetic, epigenetic, and environmental risk factors.

Conditions associated with IgE Food Allergy

  • Hives or red, itchy skin
  • Stuffy or itchy nose, sneezing or itchy, teary eyes
  • Vomiting, stomach cramps or diarrhea
  • Angioedema or swelling
  • Shortness of breath or wheezing
  • Anaphylaxis
Learn More

The IgE Inhalants Profile is a blood test that measures IgE antibodies to 16 common indoor and outdoor inhalants specific to 18 North American geographic regions. The profile also includes a total IgE measurement. Testing can help identify whether an allergen is triggering the common symptoms associated with seasonal, pet or mite allergies. These symptoms include sneezing, coughing, itchy and watery eyes, and others. The patient can experience relief with symptom management, and by avoiding ongoing exposure to the identified allergen.

Symptoms and conditions associated with IgE inhalant allergies

  • Stuffy or itchy nose, sneezing, rhinitis or sinusitis
  • Itchy, teary eyes, conjunctivitis
  • Cough, shortness of breath, wheezing, asthma
  • Skin rash or hives
Learn More

The IgE Mold Profile is a blood test that measures IgE antibodies to 15 common indoor and outdoor molds. The panel also includes a total IgE measurement. Everyone breathes in airborne mold spores, and in people with mold allergies, symptoms mainly affect the respiratory tract. Testing for mold allergies can identify whether mold is causing the symptoms. The patient can experience relief with symptom management, and by avoiding ongoing exposure to the mold source.

Symptoms and conditions associated with IgE mold allergies

  • Stuffy or itchy nose, sneezing, rhinitis or sinusitis
  • Itchy, teary eyes, conjunctivitis
  • Cough, shortness of breath, wheezing, asthma
  • Skin rash or hives

Occupations at greater risk of developing a mold allergy

  • Farmers
  • Dairyworkers
  • Loggers
  • Bakers
  • Mill workers
  • Carpenters
  • Greenhouse employees
  • Winemakers
  • Furniture repairers
Learn More